Survival rates have increased by 83%: scientists identify foods that protect the brain from dementia.

In the quest to understand the intricate workings of the human brain, scientists have long been exploring the potential protective effects of certain food components. Recent studies have highlighted the significant role of omega-3 fatty acids — nutrients abundantly found in fatty fish, nuts, and seeds — in safeguarding against neurodegenerative diseases such as motor neuron disease (MND) and frontotemporal dementia (FTD), as reported by Daily Record.

A study published in the journal Nature Neuroscience indicates that omega-3 fats may influence the progression of these debilitating diseases and potentially enhance survival rates among affected individuals.

The researchers focused on a genetic mutation known as C9orf72, the most common genetic cause of both MND and FTD. Using fruit flies carrying this mutation, the scientists observed a significant reduction in the levels of polyunsaturated fatty acids, including omega-3, in their brain cells. This deficiency mirrored findings from studies of human brain cells affected by the same mutation.

To delve deeper into the issue, the researchers increased the intake of alpha-linolenic acid (ALA) — a type of omega-3 fatty acid found in flaxseeds, walnuts, and canola oil — in the diet of the mutated flies. This dietary intervention resulted in a modest improvement in their survival rates. When the team directly introduced these fatty acids into brain cells, the results were even more pronounced: survival increased by 83%, extending the lifespan of the flies from 15 to 27.5 days.

Professor of neurodegenerative diseases, Adrian Isaacs, who led the study, emphasized the importance of the findings: "Epidemiological studies show that individuals with high omega-3 fatty acid intake have a lower risk of developing motor neuron disease. Our research provides deeper insights into the mechanisms underlying this."

Despite the promising results, transitioning from laboratory data to human application requires further research. The research team is currently focused on identifying the most effective fatty acid for human trials and developing methods to deliver sufficient amounts to the brain.

Dr. Julia Dudley from Alzheimer's Research UK highlighted the broader implications of the study's findings, noting that such conclusions could pave the way for new treatment approaches for a range of neurodegenerative diseases. This research clearly demonstrated the potential of dietary components, particularly omega-3 fatty acids, in influencing brain health and combating diseases that have long lacked effective treatments.

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