In the quest for healthier sugar alternatives, artificial sweeteners have become widely used in products such as diet sodas, sugar-free gum, and low-sugar yogurts. However, recent studies indicate that these substitutes may not be as harmless as previously thought and could significantly impact our health, reports New York Post.
A study conducted by researchers from the Karolinska Institute in Sweden and published in the journal Cell Metabolism highlighted potential cardiovascular risks associated with aspartame, a commonly used artificial sweetener.
The research team led by Professor Yihai Cao found that the consumption of aspartame by mice resulted in elevated insulin levels, which in turn contributed to the development of atherosclerosis—an accumulation of fatty plaques in the arteries. This condition is a known precursor to heart attacks and strokes.
During the study, mice were fed a diet containing 0.15% aspartame for 12 weeks, a substance that has faced significant criticism in the past, roughly equivalent to a human consuming three cans of diet soda per day. These mice exhibited larger and lipid-rich plaques in their arteries compared to those not exposed to aspartame.
Furthermore, the researchers identified the inflammatory protein CX3CL1, which remained attached to the inner lining of blood vessels at elevated insulin levels. This protein acted as a lure, attracting immune cells and promoting inflammation—a key factor in the progression of atherosclerosis.
Although these results are based on animal models, they raise important questions about the long-term effects of artificial sweeteners on human health. Professor Cao emphasized the need for further research in this area, stating: "Artificial sweeteners have infiltrated nearly all types of food, so we must understand their long-term effects on health."
Aspartame is about 200 times sweeter than sugar, allowing manufacturers to use it in minimal amounts to achieve the desired sweetness, thus reducing production costs. Despite its widespread use, in 2023, the International Agency for Research on Cancer under the World Health Organization classified aspartame as "possibly carcinogenic to humans," indicating ongoing concerns regarding its safety.
As research continues to investigate the impact of artificial sweeteners, individuals may want to consider moderating their intake and opting for natural alternatives when possible. Maintaining a balanced diet rich in whole foods remains a cornerstone of cardiovascular health.
This material is for informational purposes only and does not contain advice that may affect your health. If you experience issues, consult a specialist.